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Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy

Key points – Overall response rate was 67% with venetoclax for 36 patients with CLL refractory to or who relapsed after idelalisib; median progression free survival has not yet been reached. Common adverse events included mild gastrointestinal events and grade 3/4 cytopenias and no patients experienced tumor lysis syndrome.